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L’attività di Tadalafil si basa sull’inibizione enzimatica di PDE5 con conseguente aumento del guanosin monofosfato ciclico intracellulare. Questo meccanismo induce prolungata vasodilatazione a livello muscolare liscio. Il metabolismo epatico attraverso ossidazione produce derivati inattivi, eliminati principalmente con la bile. L’esposizione sistemica rimane stabile anche in seguito a somministrazioni ripetute. Per le sue proprietà farmacocinetiche, cialis generico italia è frequentemente inserito nei profili comparativi degli inibitori PDE5 a lunga durata.
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Knowledge Center/FAQWhat forms of payment do you accept? We accept Paypal for your convenience. Customers choosing to pay by Paypal will receive their orders in just a few days. All Paypal transactions are conducted on the secure Paypal website. We realize than not everyone is comfortable making financial transactions online. Therefore, we also accept the following forms of payment: United States Postal Money Orders. We ship these orders within 24 hours of receiving your money order in the mail. (Please note that we do not accept other money orders.) Personal or business checks. These orders will ship when your check clears our bank and may take up to three weeks. We do not accept any other form of payment. Please do not ask us to make an exception. |
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